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Opalite Health

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Helping Healthcare Providers Speak Any Language

Winter 2026Founded 20253 peopleSan Francisco, CA, USA
AI insightcan contain mistakes
Medical Interpretation AISaaSHealthcare providers, hospitals, clinicsMedium competition
Moat
Real-time voice AI in clinical workflows; medical-grade accuracy and compliance reduce liability vs. human interpreters.
Key risk
Regulatory approval and liability concerns; competing against human interpreters and legacy video remote interpretation.
Why now
Provider burnout from manual interpretation; compliance pressure (LEP regulations); AI voice quality sufficient.
Competitors
Stratus Video, CyraCom, human interpreters, legacy VRI

About

Opalite makes it easy for healthcare providers to communicate with non-English speaking patients. We’re built to work inside existing clinical workflows, so providers can communicate in real time without waiting for an interpreter or delaying care. Opalite is available instantly, 24/7, and replaces traditional interpretation services with software that’s more reliable and saves millions of dollars per year. We've built a voice AI system that is the safest, most compliant, and most accurate medical interpreter in the world.

Founders Β· 2

Cathleen Kuo
Cathleen KuoFounder

CEO of Opalite Health. Physician and AI healthcare researcher with 200+ publications. Passionate about building technology that actually moves the needle in healthcare - safer care, fewer barriers, better outcomes for everyone.

Alex Mehregan
Alex MehreganFounder
AppleBerkeley

CTO Opalite Health. Former engineer at Apple (Siri, System Experience). Berkeley EECS grad. Wrote software that touched many millions of users.

Launch

Launched on Y Combinator Β· Jan 2026
View launch post β†—

Making medical interpretation instant, reliable, and affordable at scale for hospitals and clinics.

Opalite provides an AI-powered medical interpreter integrated into clinical workflows (including EHR) to communicate with non-English-speaking patients, available instantaneously 24/7, aiming to reduce session time and interpretation costs while generating visit documentation; it is used across hospitals, community centers, home health, telehealth, and clinics in 10+ states as they prepare a large enterprise rollout.

Formerly β€œCalliope”

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