platoseed
The cure for hair loss.
At dNovo, we are curing hair loss by creating new hair, de novo. We are doing this with cellular reprogramming technology that we pioneered at Stanford and Harvard. With this technology, we can take any patient derived cell, whether it be blood, skin or fat and reprogram (convert) them into medically relevant cell types. Our first objective is to cure hair loss by using our reprogramming technology to make new hair (patent pending). This is different from everything currently available on the market because the hair loss industry is focused on maintaining the hair that you already have, but no one is trying to produce NEW hair, de novo. After hair, we envision using our cellular reprogramming technique to make any cell, any tissue or any organ on demand to replace what is lost as we age.
dNovo is a biotechnology company aiming to cure hair loss by regenerating an individual's own hair stem cells using direct reprogramming technology. It states it can generate personalized hair stem cells from a small skin sample or blood and transplant them to the scalp to restore hair growth. The company positions its approach as addressing the root cause of hair loss rather than merely slowing or disguising it.
Collect a small piece of skin or a few drops of blood at an onsite facility. Apply dNovoβs proprietary direct reprogramming factors to convert collected cells into personalized hair stem cells (and dermal papilla cells in some cases). Transplant the reprogrammed cells onto the scalp, where they are intended to regenerate hair-producing cells and initiate hair growth within 1-3 months.
Who itβs for: Individuals experiencing hair loss due to hair stem cell loss, including age-related hair miniaturization and DHT-related male pattern baldness, who are seeking a root-cause regenerative solution.
YC 2018 affiliation and multiple milestone announcements; published press coverage and institutional affiliations are mentioned.
Ernesto Lujan received his Ph.D. in Genetics from Stanford, and has published cutting edge research on regenerative medicine in Nature, Cell Stem Cell, and the Proceedings of the National Academy of Sciences. His discovery of directly reprogramming skin into neural stem cells that successfully integrated in a live mouse brain was featured in the BBC. He has received awards from the National Science Foundation, Ford Foundation, and California Institute for Regenerative Medicine.

New therapeutics to rejuvenate tissue and treat age-related diseases

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