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Granza Bio

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Reprogramming Immunity for Target-Specific Medicines

Winter 2024Founded 20247 peopleSan Francisco, CA, USA

About

Granza Bio is developing programmable therapeutics for the immune system. Our platform is built on the foundational discovery of immune “superkiller” attack particles — the natural ammunition used by cytotoxic immune cells to deliver potent, localized killing. By re-arming exhausted immune cells with newly programmed ammunition, Granza restores and enhances immune function. This approach enables a new class of treatments with the potential to transform diseases ranging from cancer to autoimmunity.

Founders · 2

Ashwin Nandakumar
Ashwin NandakumarFounder
Oxford🎓 Oxford University🎓 University of Oxford. After

Ashwin completed his PhD (DPhil) in Oncology at the University of Oxford. After completing his PhD, he began working as a Cancer Research UK post-doctoral researcher at Oxford University and also at the Institute of Cancer Research (ICR), London. He also brings experience setting up oncology clinical trials and working in oncology start-ups.

Ashwin Jainarayanan
Ashwin JainarayananFounder
Oxford🎓 University of Oxford

Granza Bio, DPhil (PhD) in Interdisciplinary Bioscience - University of Oxford

Launch

Launched on Y Combinator · Feb 2024
View launch post ↗

We engineer "attack particles" that selectively target and kill cancer cells, eliminating unwanted side effects and toxicity.

Granza Bio develops personalised cancer therapies using engineered attack particles that selectively kill cancer cells while sparing healthy tissue, aiming to cross the blood-brain barrier and enable a platform approach for multiple diseases. The launch introduces the team, the problem of treatment toxicity, and the solution’s core value of targeted cancer killing with minimal side effects.

From the original launch (Feb 2024) — may be outdated.

Formerly Zyme Therapeutics

HealthcareTherapeuticsSynthetic BiologyBiotechHealthcareTherapeuticsOncology

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