platoseed
Helping Plastic Surgeons Rebuild Fat
inSoma Bio develops bio-inspired materials for reconstructive plastic surgery, enabling the use of a patient’s own tissue and biointegrated implants. Their Fractomer biomatrix provides tissue support and shape with a thermal switch activated at body temperature, designed to reduce reliance on synthetic implants.
Fractomer Biomatrix: bio-inspired protein-based materials used to support co-injected cells or tissues, providing shape, support, and biointegration. Features a thermal switch so the material is activated at body temperature. Recombinant design manufactured without harvesting natural tissue. Aims to enable surgeons to use a patient’s own tissue instead of implants for procedures like breast and facial reconstruction.
Who it’s for: Plastic surgeons specializing in reconstructive procedures such as breast and facial reconstruction who seek tissue-based alternatives to synthetic implants.
Awards/recognitions and leadership appointments; attendance at MedTech Innovator 2025 indicates traction and visibility in the MedTech ecosystem
I am a professor of Biomedical Engineering at Duke University, and currently the Chair of the department. I work on genetically encoded biomaterials, drug delivery and point-of-care diagnostics. I have cofounded 5 companies — PhaseBio (NASDAQ: PHAS), Sentilus (acquired by Immucor in 2014), Gateway Bio, Isolere Bio and inSoma Bio,
Volumetric builds living multicellular tissues with a focus on the…

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