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Anto Biosciences

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A Foundation Model for Microbial Communities.

Fall 2025Founded 20254 peopleSan Francisco, CA, USA

About

Anto is building a foundation model for microbial communities, making the gut microbiome computable for the first time. We predict drug toxicity and efficacy across diverse populations and fix drugs so they work for everyone โ€” solving the hidden root cause of most drug failures. Founded by Arvid (Broad Institute of MIT and Harvard; Nature-published researcher who pioneered quality-aware, goal-directed sparsification) and David (Harvard Medical School Gastroenterology, J&J), second-time founders who published the breakthrough at leading machine learning AI conferences and Nature.

Founders ยท 2

Arvid E. Gollwitzer
Arvid E. GollwitzerFounder
MITHarvardETH Zurich

Founder @ Anto Bio | Researcher @ Broad, Harvard, MIT | Lecturer @ ETH Zurich

David de Gruijl
David de GruijlFounder
HarvardETH Zurich

Co-founder @ Anto. Formerly Janssen Pharmaceuticals, ETH Zurich and Gastroenterology Dept. of BWH, Harvard Medical School.

Launch

Launched on Y Combinator ยท Nov 2025
View launch post โ†—

Making the microbiome computable.

Anto Biosciences builds multimodal foundation models to predict drug toxicity and efficacy across diverse populations based on microbiome data, and to optimize molecules for broader efficacy by identifying population-specific responses and microbial pathways that drive outcomes.

Formerly โ€œAntoโ€

HealthcareArtificial IntelligenceGenerative AIBiotechGenomicsDrug discovery

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