Alfie

Acquired

Democratizing access to precision weight loss medications

Winter 2022Founded 20226 peopleNew York, NY, USA

www.joinalfie.com ↗LinkedIn ↗X ↗See on the Idea Map Healthcare momentum

About

At Alfie, we've built a rigorous virtual medical program based on the top research from Cleveland Clinic and Harvard that allows us to precisely determine which weight loss regimen and (as needed) medications will be most effective for our members in a multimodal approach. We're optimizing exercise/nutrition/medications in complex care pathways like no one else has before. Our program has been shown to be 2x more effective than standard prescription medication and 5x more effective than habit change alone. We've raised capital from Goodwater Capital, Nina Capital, Air Force Ventures, and Phoenix Club, and various super angels including the founder of OpenTrons (medical labs automation; have raised $240 mill). Also, we're a Y Combinator graduate.

From their website

as of Jun 7, 2026www.joinalfie.com ↗

Services

Alfie offers a precision metabolic health platform centered on obesity management and data-driven treatment strategies. It has been acquired by knownwell, and standalone Alfie access and affiliated clinics have been shut down as part of the integration into knownwell's care model.

Alfie’s ObesityRx technology analyzes a patient’s medical history to determine effective treatment strategies for sustainable metabolic health improvements, using a data-driven approach to balance cost and outcomes. post-acquisition, Alfie’s platform is integrated into knownwell's care model to support clinical decision-making and obesity management within a broader weight-inclusive, evidence-based metabolic health framework.

Who it’s for: Patients seeking evidence-based obesity and metabolic health management and clinicians providing obesity care within a weight-inclusive model.

Features

data-driven obesity management
AI-powered treatment recommendations
integration with clinical care teams
evidence-based metabolic health strategies
cost-outcome optimization
telehealth-enabled care

Acquired by knownwell; integration into another company’s care model; closure of standalone Alfie platform and clinics

Founders · 2

Alexander SinghFounder

Former cofounder and CEO of Alfie Health, an AI-powered precision weight loss company. Led the company to acquisition by knownwell. He's also an Investment Partner with Pioneer Fund and a Venture Partner at Not Yet Ventures.

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